• A.P. Biology Unit 1: Biochemistry
    external image Phospholipid.jpg
  • Content Standards:
    • Interactions within biological systems lead to complex properties.
    • Competition and cooperation are important aspects of biological systems.

    Students will know:
    • The subcomponents of a biological polymer and their sequence determine the properties of that polymer.
    • Interactions between molecules affect their structure and function.
    • Variation in molecular units provides cells with a wider range of functions.
    • Co-operative interactions within organisms increase efficiency in the use of energy and matter.

    Students will be able to:
    • Use models to show that the subcomponents of a biological polymer determines the properties of that polymer
    • Predict the effect of a change in the subcomponents of a biological polymer on the functionality of the molecule.
    • Analyze data to identify how molecular interactions affect structure and function (ie. enzymes)
    • Analyze data to identify fitness patterns that result from cell-cell interactions
    • Use representations and models to analyze how co-operative interactions within organisms increase the efficiency of the use of energy and matter. (ie. specialization of organelles within cell)
    • Construct explanations based on evidence how variation in molecular units provides cells with a wider range of functions.


    Lectures Reading Assignments **

    1. Introduction: Major Themes p. 1-17
    2. Scientific Method p. 18-27
    3. Water / Buffers p. 46-57
    4. Carbon / Functional Groups p. 58-67
    5. Carbohydrates / Lipids p. 68-77
    6. Proteins / Nucleic Acids p. 77-90
    7. Enzymes p. 151-161

    Labs
    • Inquiry: Behavior – Pillbugs
    • Biochemistry of Milk
    • Inquiry: Enzymes

    Case Studies
    • The Secret of popcorn
    • Sweet Truth

    Articles
    • Hormonal Sabotage (Intro to themes)
    • Water
    • Lysozyme

    Essays
    • Water
    • Carbon / Biomolecules
    • Enzymes
    • Enzyme Lab

    ** 8th edition – Campbell and Reece



1. Topic: Themes in Biology





2. Topic: Scientific Method










  • Here's a description of a fun experiment... It emphasizes the importance of controls in an experiment and the fact that each experiment must contain only a single variable!


http://www.ozy.com/good-sht/the-secret-to-baking-the-best-chocolate-cookie-science/6613.article
http://sweets.seriouseats.com/2013/12/the-food-lab-the-best-chocolate-chip-cookies.html?ref=search


  • And here's the recipe! Bon appetit!


  • Watch the following TED talk which describes the biochemistry of chocolate chip cookies.



  • And if you are wondering why chocolate chip cookies are so addictive......




3. Topic: Intro to Chemistry


  • These topics were covered in your summer work.

4. Topic: Water


  • Use models to show that the subcomponents of a biological polymer determines the properties of that polymer

  • Read the following case study which emphasizes the properties of water. Complete the questions below.

http://sciencecases.lib.buffalo.edu/cs/files/popcorn.pdf


  • This video reviews the properties of water and shows how they are dependent upon the structure of the molecule.



  • Complete this worksheet to review water.



5. Topic: Bioelements / Functional Groups


  • Follow this link to a tutorial on functional groups


http://www.phschool.com/science/biology_place/biocoach/biokit/function.html

  • Follow this link to a tutorial / review of biomolecules


http://www.phschool.com/science/biology_place/biocoach/bioprop/intro.html

  • Here is a chart which summarizes the structures and functions of functional groups.



  • Here is an excellent video to review functional groups


http://www.youtube.com/watch?v=PYlALulONE0

6. Topic: Biomolecules




  • This will provide a good introduction to organic chemistry







  • The subcomponents of a biological polymer and their sequence determine the properties of that polymer.
  • Read the following case study and use the information to answer the questions below..


http://sciencecases.lib.buffalo.edu/cs/files/sweet_truth.pdf


  • Reading Assignment and Worksheet on Polysaccharides



  • Variation in molecular units provides cells with a wider range of functions.
  • Predict the effect of a change in the subcomponents of a biological polymer on the functionality of the molecule

  • A recent article on the interaction between pectin and cellulose

http://www.sciencedaily.com/releases/2013/09/130920094225.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fplants_animals%2Fbiology+%28ScienceDaily%3A+Plants+%26+Animals+News+--+Biology%29
  • Reading Assignment and Worksheet on Proteins




  • Class Activity on Protein Folding




  • Here is a great tutorial on biochemistry. The sections on Chemistry, large molecules and enzymes contain some great questions. I will be using some of these questions on your test!

http://www.biology.arizona.edu/biochemistry/biochemistry.html

  • Here is a website with interactive animations in Biochemistry. Try enzyme specificity and protein folding


http://www.wiley.com/legacy/college/boyer/0470003790/

  • Watch Mr. Anderson's video to review biomolecules.


Article: September 9, 2013: New camouflage coating fabricated from squid protein

http://www.sciencedaily.com/releases/2013/09/130909172215.htm

Article: September 13, 2013: Biochemists Resurrect 'Molecular Fossils': Findings Challenge Assumptions About Origins of Life


http://www.sciencedaily.com/releases/2013/09/130913185848.htm

Article: September 16, 2013:Scientists Discover Cosmic Factory for Making Building Blocks of Life

http://www.sciencedaily.com/releases/2013/09/130915134341.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fplants_animals%2Fbiology+%28ScienceDaily%3A+Plants+%26+Animals+News+--+Biology%29

7. Topic: Enzymes


  • Interactions between molecules affect their structure and function.
  • Co-operative interactions within organisms increase efficiency in the use of energy and matter.
  • Analyze data to identify how molecular interactions affect structure and function (ie. enzymes)




  • Here is a simulation of the enzyme lab which measures the amount of hydrogen peroxide consumed rather than the amount of oxygen produced.

http://www.ucopenaccess.org/courses/APBioLabs/course/index.html

  • Watch Mr. Anderson's video on enzymes.


  • Analysis of Enzyme Essays